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Titel:

Molecular Assessment of Staphylococcus Aureus Strains in STAT3 Hyper-IgE Syndrome Patients.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Schwierzeck, Vera; Effner, Renate; Abel, Felicitas; Reiger, Matthias; Notheis, Gundula; Held, Jürgen; Simon, Valeska; Dintner, Sebastian; Hoffmann, Reinhard; Hagl, Beate; Huebner, Johannes; Mellmann, Alexander; Renner, Ellen D
Abstract:
Hyper-IgE syndromes (HIES) are a group of inborn errors of immunity (IEI) caused by monogenic defects such as in the gene STAT3 (STAT3-HIES). Patients suffering from HIES show an increased susceptibility to Staphylococcus aureus (S. aureus) including skin abscesses and pulmonary infections. To assess if the underlying immune defect of STAT3-HIES patients influences the resistance patterns, pathogenicity factors or strain types of S. aureus. We characterized eleven S. aureus strains isolated from...     »
Zeitschriftentitel:
J Clin Immunol
Jahr:
2022
Band / Volume:
42
Heft / Issue:
6
Seitenangaben Beitrag:
1301-1309
Volltext / DOI:
doi:10.1007/s10875-022-01293-7
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35655107
Print-ISSN:
0271-9142
TUM Einrichtung:
611; Klinik und Poliklinik für Kinder- und Jugendmedizin
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