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Titel:

Elevations in blood glucose before and after the appearance of islet autoantibodies in children.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Warncke, Katharina; Weiss, Andreas; Achenbach, Peter; von dem Berge, Thekla; Berner, Reinhard; Casteels, Kristina; Groele, Lidia; Hatzikotoulas, Konstantinos; Hommel, Angela; Kordonouri, Olga; Elding Larsson, Helena; Lundgren, Markus; Marcus, Benjamin A; Snape, Matthew D; Szypowska, Agnieszka; Todd, John A; Bonifacio, Ezio; Ziegler, Anette-G
Abstract:
The etiology of type 1 diabetes has polygenic and environmental determinants that lead to autoimmune responses against pancreatic β cells and promote β cell death. The autoimmunity is considered silent without metabolic consequences until late preclinical stages,and it remains unknown how early in the disease process the pancreatic β cell is compromised. To address this, we investigated preprandial nonfasting and postprandial blood glucose concentrations and islet autoantibody development in 1,0...     »
Zeitschriftentitel:
J Clin Invest
Jahr:
2022
Band / Volume:
132
Heft / Issue:
20
Volltext / DOI:
doi:10.1172/JCI162123
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36250461
Print-ISSN:
0021-9738
TUM Einrichtung:
Klinik und Poliklinik für Kinder- und Jugendmedizin
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