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Title:

Molecular Profiling in Pancreatic Cancer: Current Role and Its Impact on Primary Surgery.

Document type:
Journal Article; Review
Author(s):
Mota Reyes, Carmen; Doğruöz, Alper; Istvanffy, Rouzanna; Friess, Helmut; Ceyhan, Güralp O; Demir, Ihsan Ekin
Abstract:
Background: The advent of next-generation sequencing technologies has enabled the identification of molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) with different biological traits and clinically targetable features. Summary: Although current chemotherapy trials are currently exploiting this knowledge, these molecular subtypes have not yet sufficiently caught the attention of surgeons. In fact, integration of these molecular subtypes into the timing of surgery can in theory improve...     »
Journal title abbreviation:
Visc Med
Year:
2022
Journal volume:
38
Journal issue:
1
Pages contribution:
37-41
Fulltext / DOI:
doi:10.1159/000519755
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35295890
Print-ISSN:
2297-4725
TUM Institution:
Klinik und Poliklinik für Chirurgie
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