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Titel:

Correlation of Transcriptomics and FDG-PET SUVmax Indicates Reciprocal Expression of Stemness-Related Transcription Factor and Neuropeptide Signaling Pathways in Glucose Metabolism of Ewing Sarcoma.

Dokumenttyp:
Journal Article
Autor(en):
Prexler, Carolin; Knape, Marie Sophie; Erlewein-Schweizer, Janina; Roll, Wolfgang; Specht, Katja; Woertler, Klaus; Weichert, Wilko; von Luettichau, Irene; Rossig, Claudia; Hauer, Julia; Richter, Guenther H S; Weber, Wolfgang; Burdach, Stefan
Abstract:
BACKGROUND: In Ewing sarcoma (EwS), long-term treatment effects and poor survival rates for relapsed or metastatic cases require individualization of therapy and the discovery of new treatment methods. Tumor glucose metabolic activity varies significantly between patients, and FDG-PET signals have been proposed as prognostic factors. However, the biological basis for the generally elevated but variable glucose metabolism in EwS is not well understood. METHODS: We retrospectively included 19 EwS...     »
Zeitschriftentitel:
Cancers (Basel)
Jahr:
2022
Band / Volume:
14
Heft / Issue:
23
Volltext / DOI:
doi:10.3390/cancers14235999
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36497479
TUM Einrichtung:
1473; Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Diagnostische und Interventionelle Radiologie ; Klinik und Poliklinik für Kinder- und Jugendmedizin; Klinik und Poliklinik für Nuklearmedizin
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