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Titel:

The Influence of Specific Activity on the Biodistribution of 18F-rhPSMA-7.3: A Retrospective Analysis of Clinical PET Data.

Dokumenttyp:
Journal Article
Autor(en):
Langbein, Thomas; Wurzer, Alexander; Gafita, Andrei; Robertson, Andrew; Wang, Hui; Arçay, Ayça; Herz, Michael; Wester, Hans-Juergen; Weber, Wolfgang A; Eiber, Matthias
Abstract:
We investigated whether the time between synthesis and injection and the resulting decrease in specific activity affects the normal-organ and tumor uptake of the PSMA ligand 18F-rhPSMA-7.3 in patients with prostate cancer. Methods: The biodistribution of 18F-rhPSMA-7.3 on PET/CT scans obtained with a high specific activity (median, 178.9 MBq/µg; n = 42) and a low specific activity (median, 19.3 MBq/µg; n = 42) was compared. Results: Tracer uptake by the parotid gland, submandibular gland, and...     »
Zeitschriftentitel:
J Nucl Med
Jahr:
2022
Band / Volume:
63
Heft / Issue:
5
Seitenangaben Beitrag:
742-745
Volltext / DOI:
doi:10.2967/jnumed.121.262471
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34385338
Print-ISSN:
0161-5505
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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