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- Titel:
Hypoglossal Nerve Stimulation Usage by Therapy Nonresponders.
- Dokumenttyp:
- Journal Article; Multicenter Study
- Autor(en):
- Coca, Kimberly K; Heiser, Clemens; Huntley, Colin; Boon, Maurits; de Vries, Nico; Mamidala, Madhu; Gillespie, M Boyd
- Abstract:
- OBJECTIVE: The purpose of this study is to examine differences in therapy usage and outcomes of therapy between responder (R) and nonresponder (NR) groups in an international, multicenter prospective registry of patients undergoing hypoglossal nerve stimulation for obstructive sleep apnea (OSA). STUDY DESIGN: Database analysis (level III). SETTING: International, multicenter registry. METHODS: The studied registry prospectively collects data pre- and postimplantation, including sleep parameters, Epworth score, patient experience, and safety questions, over the course of 12 months. Patients are defined as a "responder" based on Sher criteria, which require a final apnea-hypopnea index (AHI) of ≤20 and a final AHI reduction of >50% at their 12-month follow-up. RESULTS: Overall, there were 497 (69%) R and 220 (31%) NR. Most patients in both groups experienced improvement in quality of life following implantation (96% of R; 77% of NR) with reductions in oxygen desaturation index and Epworth score. At final follow-up, the R group demonstrated significantly better adherence to recommended therapy (>4 hours/night) (P = .001), average hours of nightly use (P = .001), final Epworth scores (P = .001), and degree of subjective improvement (P < .001). CONCLUSION: Patients classified as NR to upper airway stimulation continue to use therapy with improvement in percent time of sleep with O2 <90%, reduction in daytime sleepiness, and improvement in quality of life. Therefore, ongoing usage of the device should be encouraged in NR patients who note improvement while integrating additional strategies to lower the long-term effects of OSA.
- Zeitschriftentitel:
- Otolaryngol Head Neck Surg
- Jahr:
- 2022
- Band / Volume:
- 166
- Heft / Issue:
- 4
- Seitenangaben Beitrag:
- 786-790
- Volltext / DOI:
- doi:10.1177/01945998211036867
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/34372740
- Print-ISSN:
- 0194-5998
- TUM Einrichtung:
- Hals-Nasen-Ohrenklinik und Poliklinik
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