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Titel:

Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue.

Dokumenttyp:
Journal Article
Autor(en):
Honecker, Julius; Ruschke, Stefan; Seeliger, Claudine; Laber, Samantha; Strobel, Sophie; Pröll, Priska; Nellaker, Christoffer; Lindgren, Cecilia M; Kulozik, Ulrich; Ecker, Josef; Karampinos, Dimitrios C; Claussnitzer, Melina; Hauner, Hans
Abstract:
BACKGROUND: The adipocyte-hypertrophy associated remodeling of fat cell function is considered causal for the development of metabolic disorders. A better understanding of transcriptome and fatty acid (FA) related alterations with adipocyte hypertrophy combined with less-invasive strategies for the detection of the latter can help to increase the prognostic and diagnostic value of adipocyte size and FA composition as markers for metabolic disease. METHODS: To clarify adipocyte-hypertrophy associ...     »
Zeitschriftentitel:
EBioMedicine
Jahr:
2022
Band / Volume:
79
Volltext / DOI:
doi:10.1016/j.ebiom.2022.104020
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35490555
TUM Einrichtung:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin; Institut für Diagnostische und Interventionelle Radiologie
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