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Title:

AROMA: real-world global registry of dupilumab for chronic rhinosinusitis with nasal polyps.

Document type:
Article; Journal Article
Author(s):
Siddiqui, Shahid; Bachert, Claus; Chaker, Adam M; Han, Joseph K; Hellings, Peter W; Peters, Anju T; Heffler, Enrico; Kamat, Siddhesh; Zhang, Haixin; Nash, Scott; Khan, Asif H; De Prado Gomez, Lucia; Jacob-Nara, Juby A; Rowe, Paul J; Deniz, Yamo
Abstract:
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a predominantly type 2 inflammatory disease of the nasal and paranasal sinuses. Dupilumab is a monoclonal antibody that blocks the shared receptor component for interleukin-4 and interleukin-13, which are key and central drivers of type 2 inflammation. In clinical trials, dupilumab significantly improved objective and patient-reported measures of CRSwNP versus placebo and was well tolerated. Dupilumab is approved in the European Union, USA and...     »
Journal title abbreviation:
ERJ Open Res
Year:
2022
Journal volume:
8
Journal issue:
4
Fulltext / DOI:
doi:10.1183/23120541.00085-2022
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36451848
TUM Institution:
Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde (Prof. Wollenberg); Lehrstuhl für Molekulare Allergologie und Umweltforschung (Prof. Schmidt-Weber)
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