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Titel:

An integrated device for fast and sensitive immunosuppressant detection.

Dokumenttyp:
Article; Journal Article
Autor(en):
Tombelli, Sara; Trono, Cosimo; Berneschi, Simone; Berrettoni, Chiara; Giannetti, Ambra; Bernini, Romeo; Persichetti, Gianluca; Testa, Genni; Orellana, Guillermo; Salis, Francesca; Weber, Susanne; Luppa, Peter B; Porro, Giampiero; Quarto, Giovanna; Schubert, Markus; Berner, Marcel; Freitas, Paulo P; Cardoso, Susana; Franco, Fernando; Silverio, Vânia; Lopez-Martinez, Maria; Hilbig, Urs; Freudenberger, Kathrin; Gauglitz, Günter; Becker, Holger; Gärtner, Claudia; O'Connell, Mark T; Baldini, Francesc...     »
Abstract:
The present paper describes a compact point of care (POC) optical device for therapeutic drug monitoring (TDM). The core of the device is a disposable plastic chip where an immunoassay for the determination of immunosuppressants takes place. The chip is designed in order to have ten parallel microchannels allowing the simultaneous detection of more than one analyte with replicate measurements. The device is equipped with a microfluidic system, which provides sample mixing with the necessary chem...     »
Zeitschriftentitel:
Anal Bioanal Chem
Jahr:
2022
Band / Volume:
414
Heft / Issue:
10
Seitenangaben Beitrag:
3243-3255
Volltext / DOI:
doi:10.1007/s00216-021-03847-x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34936009
Print-ISSN:
1618-2642
TUM Einrichtung:
Institut für Klinische Chemie und Pathobiochemie
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