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Title:

Common and specific large-scale brain changes in major depressive disorder, anxiety disorders, and chronic pain: a transdiagnostic multimodal meta-analysis of structural and functional MRI studies.

Document type:
Journal Article; Meta-Analysis
Author(s):
Brandl, Felix; Weise, Benedikt; Mulej Bratec, Satja; Jassim, Nazia; Hoffmann Ayala, Daniel; Bertram, Teresa; Ploner, Markus; Sorg, Christian
Abstract:
Major depressive disorder (MDD), anxiety disorders (ANX), and chronic pain (CP) are closely-related disorders with both high degrees of comorbidity among them and shared risk factors. Considering this multi-level overlap, but also the distinct phenotypes of the disorders, we hypothesized both common and disorder-specific changes of large-scale brain systems, which mediate neural mechanisms and impaired behavioral traits, in MDD, ANX, and CP. To identify such common and disorder-specific brain ch...     »
Journal title abbreviation:
Neuropsychopharmacology
Year:
2022
Journal volume:
47
Journal issue:
5
Pages contribution:
1071-1080
Fulltext / DOI:
doi:10.1038/s41386-022-01271-y
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35058584
Print-ISSN:
0893-133X
TUM Institution:
Klinik und Poliklinik für Neurologie (Prof. Hemmer); Klinik und Poliklinik für Psychiatrie und Psychotherapie (Prof. Priller); Professur für Human Pain Research (Prof. Ploner); Professur für Neuroradiologie (Prof. Zimmer)
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