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Titel:

Recent Advances in Copper-Based Organic Complexes and Nanoparticles for Tumor Theranostics.

Dokumenttyp:
Journal Article; Review
Autor(en):
Tsymbal, Sergey; Li, Ge; Agadzhanian, Nikol; Sun, Yuhao; Zhang, Jiazhennan; Dukhinova, Marina; Fedorov, Viacheslav; Shevtsov, Maxim
Abstract:
Treatment of drug-resistant forms of cancer requires consideration of their hallmark features, such as abnormal cell death mechanisms or mutations in drug-responding molecular pathways. Malignant cells differ from their normal counterparts in numerous aspects, including copper metabolism. Intracellular copper levels are elevated in various cancer types, and this phenomenon could be employed for the development of novel oncotherapeutic approaches. Copper maintains the cell oxidation levels, regul...     »
Zeitschriftentitel:
Molecules
Jahr:
2022
Band / Volume:
27
Heft / Issue:
20
Volltext / DOI:
doi:10.3390/molecules27207066
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36296659
Print-ISSN:
1420-3049
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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