User: Guest  Login
More Searchfields
Simple search
Title:

Comparative analysis of extracellular vesicle isolation methods from human AML bone marrow cells and AML cell lines.

Document type:
Article; Journal Article
Author(s):
Lang, Jonas B; Buck, Michèle C; Rivière, Jennifer; Stambouli, Oumaima; Sachenbacher, Ken; Choudhary, Purva; Dietz, Hendrik; Giebel, Bernd; Bassermann, Florian; Oostendorp, Robert A J; Götze, Katharina S; Hecker, Judith S
Abstract:
Cellular crosstalk between hematopoietic stem/progenitor cells and the bone marrow (BM) niche is vital for the development and maintenance of myeloid malignancies. These compartments can communicate via bidirectional transfer of extracellular vesicles (EVs). EV trafficking in acute myeloid leukemia (AML) plays a crucial role in shaping the BM microenvironment into a leukemia-permissive niche. Although several EV isolation methods have been developed, it remains a major challenge to define the mo...     »
Journal title abbreviation:
Front Oncol
Year:
2022
Journal volume:
12
Fulltext / DOI:
doi:10.3389/fonc.2022.949261
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36263223
Print-ISSN:
2234-943X
TUM Institution:
Klinik und Poliklinik für Innere Medizin III, Hämatologie und Onkologie
 BibTeX