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Title:

Mitochondria in Neuronal Health: From Energy Metabolism to Parkinson's Disease.

Document type:
Review; Journal Article; Review
Author(s):
Murali Mahadevan, Hariharan; Hashemiaghdam, Arsalan; Ashrafi, Ghazaleh; Harbauer, Angelika Bettina
Abstract:
Mitochondria are the main suppliers of neuronal adenosine triphosphate and play a critical role in brain energy metabolism. Mitochondria also serve as Ca2+ sinks and anabolic factories and are therefore essential for neuronal function and survival. Dysregulation of neuronal bioenergetics is increasingly implicated in neurodegenerative disorders, particularly Parkinson's disease. This review describes the role of mitochondria in energy metabolism under resting conditions and during synaptic trans...     »
Journal title abbreviation:
Adv Biol (Weinh)
Year:
2021
Journal volume:
5
Journal issue:
9
Fulltext / DOI:
doi:10.1002/adbi.202100663
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34382382
TUM Institution:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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