Benutzer: Gast  Login
Titel:

Binding of phosphatidylserine-positive microparticles by PBMCs classifies disease severity in COVID-19 patients.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Rausch, Lisa; Lutz, Konstantin; Schifferer, Martina; Winheim, Elena; Gruber, Rudi; Oesterhaus, Elina F; Rinke, Linus; Hellmuth, Johannes C; Scherer, Clemens; Muenchhoff, Maximilian; Mandel, Christopher; Bergwelt-Baildon, Michael; Simons, Mikael; Straub, Tobias; Krug, Anne B; Kranich, Jan; Brocker, Thomas
Abstract:
Infection with SARS-CoV-2 is associated with thromboinflammation, involving thrombotic and inflammatory responses, in many COVID-19 patients. In addition, immune dysfunction occurs in patients characterised by T cell exhaustion and severe lymphopenia. We investigated the distribution of phosphatidylserine (PS), a marker of dying cells, activated platelets and platelet-derived microparticles (PMP), during the clinical course of COVID-19. We found an unexpectedly high amount of blood cells loaded...     »
Zeitschriftentitel:
J Extracell Vesicles
Jahr:
2021
Band / Volume:
10
Heft / Issue:
14
Volltext / DOI:
doi:10.1002/jev2.12173
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34854246
TUM Einrichtung:
608; Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
 BibTeX