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Title:

Different Effects of Lifestyle Intervention in High- and Low-Risk Prediabetes: Results of the Randomized Controlled Prediabetes Lifestyle Intervention Study (PLIS).

Document type:
Journal Article
Author(s):
Fritsche, Andreas; Wagner, Robert; Heni, Martin; Kantartzis, Kostantinos; Machann, Jürgen; Schick, Fritz; Lehmann, Rainer; Peter, Andreas; Dannecker, Corinna; Fritsche, Louise; Valenta, Vera; Schick, Renate; Nawroth, Peter Paul; Kopf, Stefan; Pfeiffer, Andreas Fh; Kabisch, Stefan; Dambeck, Ulrike; Stumvoll, Michael; Blüher, Matthias; Birkenfeld, Andreas L; Schwarz, Peter; Hauner, Hans; Clavel, Julia; Seißler, Jochen; Lechner, Andreas; Müssig, Karsten; Weber, Katharina; Laxy, Michael; Bornstein,...     »
Abstract:
Lifestyle intervention (LI) can prevent type 2 diabetes, but response to LI varies depending on risk subphenotypes. We tested whether individuals with prediabetes with low risk (LR) benefit from conventional LI and individuals with high risk (HR) benefit from an intensification of LI in a multicenter randomized controlled intervention over 12 months with 2 years' follow-up. A total of 1,105 individuals with prediabetes based on American Diabetes Association glucose criteria were stratified into...     »
Journal title abbreviation:
Diabetes
Year:
2021
Journal volume:
70
Journal issue:
12
Pages contribution:
2785-2795
Fulltext / DOI:
doi:10.2337/db21-0526
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34531293
Print-ISSN:
0012-1797
TUM Institution:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin
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