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Title:

A computational framework for modeling cell-matrix interactions in soft biological tissues

Document type:
Zeitschriftenaufsatz
Author(s):
Eichinger JF, Grill MJ, Davoodi Kermani I, Aydin RC, Wall WA, Humphrey JD, Cyron CJ
Abstract:
Living soft tissues appear to promote the de-velopment and maintenance of a preferred mechanicalstate within a defined tolerance around a so-called set-point. This phenomenon is often referred to as mechan-ical homeostasis. In contradiction to the prominent roleof mechanical homeostasis in various (patho)physiolo-gical processes, its underlying micromechanical mecha-nisms acting on the level of individual cells and fibersremain poorly understood, especially, how these mech-anisms on the microsca...     »
Keywords:
mechanical homeostasis; growth andremodeling; cell-extracellular matrix interaction; discrete fiber model; finite element method
Dewey Decimal Classification:
620 Ingenieurwissenschaften
Journal title:
Biomechanics and Modeling in Mechanobiology
Year:
2021
Covered by:
Scopus
Fulltext / DOI:
doi:10.1007/s10237-021-01480-2
Status:
Verlagsversion / published
Date of publication:
25.06.2021
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