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Title:

Modulating the Bioactivity of Mucin Hydrogels with Crosslinking Architecture

Document type:
Zeitschriftenaufsatz
Author(s):
Jiang, Kun; Yan, Hongji; Rickert, Carolin; Marczynski, Matthias; Sixtensson, Kajsa; Vilaplana, Francisco; Lieleg, Oliver; Crouzier, Thomas
Abstract:
Hydrogels made of crosslinked macromolecules used in regenerative medi-cine technologies can be designed to affect the fate of surrounding cells and tissues in defined ways. Their function typically depends on the type and number of bioactive moieties such as receptor ligands present in the hydrogel. However, the detail in how such moieties are presented to cells can also be instrumental. In this work, how the crosslinking architecture of a hydrogel can affect its bioactivity is explored. It is...     »
Keywords:
biomaterials, degradation, hydrogels structure, immune response, mucin
Dewey Decimal Classification:
500 Naturwissenschaften
Journal title:
Advanced Functional Materials
Year:
2021
Journal volume:
31
Journal issue:
10
Pages contribution:
2008428
Covered by:
Scopus
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1002/adfm.202008428
WWW:
https://onlinelibrary.wiley.com/doi/pdf/10.1002/adfm.202008428
Publisher:
Wiley
E-ISSN:
1616-301X1616-3028
Date of publication:
27.01.2021
TUM Institution:
Professur für Biomechanik
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