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Boesen, Benedikt;Heider, Anna;O’Shea, Jack M.;Groll, Michael;Bach, Thorsten;Zeymer, Cathleen
Enantiodivergent Evolution of a De Novo Protein for Enzymatic [2 + 2] Photocycloaddition Activity
ACS Catalysis
2026
16
7
6589-6599

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Wagner Egea, Paula;Delhommel, Florent;Mustafa, Ghulam;Leiss-Maier, Florian;Klimper, Lisa;Badmann, Thomas;Heider, Anna;Wille, Idoia;Groll, Michael;Sattler, Michael;Zeymer, Cathleen
Modular protein scaffold architecture and AI-guided sequence optimization facilitate de novo metalloenzyme engineering
Structure
2026
34
1
32-44.e6

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Bahukhandi, Srishti B.;Klein, Andreas S.;Mustafa, Ghulam;Weyh, Maria;Walter, Alexandra;Thyrhaug, Erling;Hauer, Jürgen;Storch, Golo;Zeymer, Cathleen
The Natural Redox Cofactor Pyrroloquinoline Quinone (PQQ) Enables Photocatalytic Radical Cyclizations
Angewandte Chemie International Edition
2025

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Klein, Andreas Sebastian;Leiss-Maier, Florian;Mühlhofer, Rahel;Boesen, Benedikt;Mustafa, Ghulam;Kugler, Hannah;Zeymer, Cathleen
A De Novo Metalloenzyme for Cerium Photoredox Catalysis
Journal of the American Chemical Society
2024