PURPOSE: To develop a methodology to simultaneously perform single echo Dixon water-fat imaging and susceptibility-weighted imaging (SWI) based on a single echo time (TE) ultra-short echo time (UTE) (sUTE) scan to assess vertebral fractures and degenerative bone changes in the thoracolumbar spine. METHODS: A methodology was developed to solve the smoothness-constrained inverse water-fat problem to separate water and fat while removing unwanted low-frequency phase terms. Additionally, the corrected UTE phase was used for SWI. UTE imaging (TE: 0.14 ms, 3T MRI) was performed in the lumbar spine of nine patients with vertebral fractures and bone marrow edema (BME). All images were reviewed by two radiologists. Water- and fat-separated images were analyzed in comparison with short-tau inversion recovery (STIR) and with respect to BME visibility. The visibility of fracture lines and cortical outlining of the UTE magnitude images were analyzed in comparison with computed tomography. RESULTS: Unwanted phase components, dominated by the B1 phase, were removed from the UTE phase images. The rating of the diagnostic quality of BME visualization showed a high preference for the sUTE-Dixon water- and fat-separated images in comparison with STIR. The UTE magnitude images enabled better visualizing fracture lines compared with STIR and slightly better visibility of cortical outlining. With increasing SWI weighting osseous structures and fatty tissues were enhanced. CONCLUSION: The proposed sUTE-Dixon-SWI methodology allows the removal of unwanted low-frequency phases and enables water-fat separation and SWI processing from a single complex UTE image. The methodology can be used for the simultaneous assessment of vertebral fractures and BME of the thoracolumbar spine.      «

PURPOSE: To develop a methodology to simultaneously perform single echo Dixon water-fat imaging and susceptibility-weighted imaging (SWI) based on a single echo time (TE) ultra-short echo time (UTE) (sUTE) scan to assess vertebral fractures and degenerative bone changes in the thoracolumbar spine. METHODS: A methodology was developed to solve the smoothness-constrained inverse water-fat problem to separate water and fat while removing unwanted low-frequency phase terms. Additionally, the correct...     »