2D/3D registration of freehand SPECT and planar scintigraphy for clinical evaluation of 3D thyroid scintigraphy

Thyroid planar scintigraphy is a standard technique in Nuclear Medicine. The clear information it provides it has allowed it to live for decades. Freehand SPECT has been introduced lately as a 3D imaging modality for small anatomies []. In this work, the freehand SPECT technology is applied for the first time for 3D thyroid scintigraphy. A first trial in 10 thyroid patients (40-78y, mean 61) was performed for the purposes of testing and evaluation of this technology in a pilot study setup. For validation a 2D/3D registration method was designed and implemented in order to compared conventional 2D thyroid scintigraphy with the new 3D freehand SPECT images. Further the accuracy of the 2D/3D registration appli-cation was evaluated with a synthetic 3D thyroid shape and known rigid transformation. The 2D/3D registration for the synthetic data were bold and the ones of the patient data sets reveal that the freehand SPECT is a promising approach that may open new doors in Nuclear Medicine.     «

Thyroid planar scintigraphy is a standard technique in Nuclear Medicine. The clear information it provides it has allowed it to live for decades. Freehand SPECT has been introduced lately as a 3D imaging modality for small anatomies []. In this work, the freehand SPECT technology is applied for the first time for 3D thyroid scintigraphy. A first trial in 10 thyroid patients (40-78y, mean 61) was performed for the purposes of testing and evaluation of this technology in a pilot study setup. For v...     »