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Titel:

Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Regensburger, Adrian P; Fonteyne, Lina M; Jüngert, Jörg; Wagner, Alexandra L; Gerhalter, Teresa; Nagel, Armin M; Heiss, Rafael; Flenkenthaler, Florian; Qurashi, Matthias; Neurath, Markus F; Klymiuk, Nikolai; Kemter, Elisabeth; Fröhlich, Thomas; Uder, Michael; Woelfle, Joachim; Rascher, Wolfgang; Trollmann, Regina; Wolf, Eckhard; Waldner, Maximilian J; Knieling, Ferdinand
Abstract:
Biomarkers for monitoring of disease progression and response to therapy are lacking for muscle diseases such as Duchenne muscular dystrophy. Noninvasive in vivo molecular imaging with multispectral optoacoustic tomography (MSOT) uses pulsed laser light to induce acoustic pressure waves, enabling the visualization of endogenous chromophores. Here we describe an application of MSOT, in which illumination in the near- and extended near-infrared ranges from 680-1,100 nm enables the visualization an...     »
Zeitschriftentitel:
Nat Med
Jahr:
2019
Band / Volume:
25
Heft / Issue:
12
Seitenangaben Beitrag:
1905-1915
Volltext / DOI:
doi:10.1038/s41591-019-0669-y
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31792454
Print-ISSN:
1078-8956
TUM Einrichtung:
1693; 5; Klinik und Poliklinik für Innere Medizin I, Kardiologie
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