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Titel:

Sorting and magnetic-based isolation of reticulated platelets from peripheral blood.

Dokumenttyp:
Article
Autor(en):
Bernlochner, Isabell; Klug, Melissa; Larasati, Ditya; Von Scheidt, Moritz; Santovito, Donato; Hristov, Michael; Weber, Christian; Laugwitz, Karl-Ludwig; Bongiovanni, Dario
Abstract:
Reticulated Platelets (RPs) are large, RNA-rich, prothrombotic and hyperactive platelets known to be elevated in high-risk populations such as diabetics and patients with acute coronary syndrome. High levels of RPs correlate with mortality and adverse cardiovascular events in patients with coronary artery disease as well as with an insufficient antiplatelet response to thienopyridines and aspirin after percutaneous coronary interventions, making them an appealing drug target. However, processing...     »
Zeitschriftentitel:
Platelets
Jahr:
2021
Band / Volume:
32
Heft / Issue:
1
Seitenangaben Beitrag:
113-119
Volltext / DOI:
doi:10.1080/09537104.2020.1724923
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32046562
Print-ISSN:
0953-7104
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert); Klinik und Poliklinik für Innere Medizin I, Kardiologie
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