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Titel:

Genetically encoded Ca2+ -sensor reveals details of porcine endothelial cell activation upon contact with human serum.

Dokumenttyp:
Article; Early Access; Journal Article
Autor(en):
Wuensch, Annegret; Kameritsch, Petra; Sfriso, Riccardo; Jemiller, Eva-Maria; Bähr, Andrea; Kurome, Mayuko; Kessler, Barbara; Kemter, Elisabeth; Kupatt, Christian; Reichart, Bruno; Rieben, Robert; Wolf, Eckhard; Klymiuk, Nikolai
Abstract:
The activation of the endothelial surface in xenografts is still a poorly understood process and the consequences are unpredictable. The role of Ca2+ -messaging during the activation of endothelial cells is well recognized and routinely measured by synthetic Ca2+ -sensitive fluorophors. However, these compounds require fresh loading immediately before each experiment and in particular when grown in state-of-the-art 3D cell culture systems, endothelial cells are difficult to access with such sens...     »
Zeitschriftentitel:
Xenotransplantation
Jahr:
2020
Band / Volume:
27
Heft / Issue:
5
Volltext / DOI:
doi:10.1111/xen.12585
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32056300
Print-ISSN:
0908-665X
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie)
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