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Titel:

Mucus threads from surface goblet cells clear particles from the airways.

Dokumenttyp:
Article; Journal Article
Autor(en):
Ermund, Anna; Meiss, Lauren N; Dolan, Brendan; Jaudas, Florian; Ewaldsson, Lars; Bähr, Andrea; Klymiuk, Nikolai; Hansson, Gunnar C
Abstract:
BACKGROUND: The mucociliary clearance system driven by beating cilia protects the airways from inhaled microbes and particles. Large particles are cleared by mucus bundles made in submucosal glands by parallel linear polymers of the MUC5B mucins. However, the structural organization and function of the mucus generated in surface goblet cells are poorly understood. METHODS: The origin and characteristics of different mucus structures were studied on live tissue explants from newborn wild-type (WT...     »
Zeitschriftentitel:
Respir Res
Jahr:
2021
Band / Volume:
22
Heft / Issue:
1
Volltext / DOI:
doi:10.1186/s12931-021-01898-3
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34823518
Print-ISSN:
1465-9921
TUM Einrichtung:
1693; Klinik und Poliklinik für Innere Medizin I, Kardiologie
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