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Title:

Cas9-expressing chickens and pigs as resources for genome editing in livestock.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Rieblinger, Beate; Sid, Hicham; Duda, Denise; Bozoglu, Tarik; Klinger, Romina; Schlickenrieder, Antonina; Lengyel, Kamila; Flisikowski, Krzysztof; Flisikowska, Tatiana; Simm, Nina; Grodziecki, Alessandro; Perleberg, Carolin; Bähr, Andrea; Carrier, Lucie; Kurome, Mayuko; Zakhartchenko, Valeri; Kessler, Barbara; Wolf, Eckhard; Kettler, Lutz; Luksch, Harald; Hagag, Ibrahim T; Wise, Daniel; Kaufman, Jim; Kaufer, Benedikt B; Kupatt, Christian; Schnieke, Angelika; Schusser, Benjamin
Abstract:
Genetically modified animals continue to provide important insights into the molecular basis of health and disease. Research has focused mostly on genetically modified mice, although other species like pigs resemble the human physiology more closely. In addition, cross-species comparisons with phylogenetically distant species such as chickens provide powerful insights into fundamental biological and biomedical processes. One of the most versatile genetic methods applicable across species is CRIS...     »
Journal title abbreviation:
Proc Natl Acad Sci U S A
Year:
2021
Journal volume:
118
Journal issue:
10
Fulltext / DOI:
doi:10.1073/pnas.2022562118
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33658378
Print-ISSN:
0027-8424
TUM Institution:
1693
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