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Titel:

Airway Administration of Flagellin Regulates the Inflammatory Response to Pseudomonas aeruginosa.

Dokumenttyp:
Journal Article
Autor(en):
López-Gálvez, Raquel; Fleurot, Isabelle; Chamero, Pablo; Trapp, Sascha; Olivier, Michel; Chevaleyre, Claire; Barc, Céline; Riou, Mickael; Rossignol, Christelle; Guillon, Antoine; Si-Tahar, Mustapha; May, Tobias; Barbry, Pascal; Bähr, Andrea; Klymiuk, Nikolai; Sirard, Jean-Claude; Caballero, Ignacio
Abstract:
Excessive lung inflammation and airway epithelial damage are hallmarks of human inflammatory lung diseases, such as cystic fibrosis (CF). Enhancement of innate immunity provides protection against pathogens while reducing lung-damaging inflammation. However, the mechanisms underlying innate immunity-mediated protection in the lung remain mysterious, in part because of the lack of appropriate animal models for these human diseases. TLR5 (Toll-like receptor 5) stimulation by its specific ligand, t...     »
Zeitschriftentitel:
Am J Respir Cell Mol Biol
Jahr:
2021
Band / Volume:
65
Heft / Issue:
4
Seitenangaben Beitrag:
378-389
Volltext / DOI:
doi:10.1165/rcmb.2021-0125OC
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34102087
Print-ISSN:
1044-1549
TUM Einrichtung:
1693; Klinik und Poliklinik für Innere Medizin I, Kardiologie
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