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Title:

Microbiota-associated Risk Factors for Clostridioides difficile Acquisition in Hospitalized Patients: A Prospective, Multicentric Study.

Document type:
Journal Article
Author(s):
Solbach, Philipp; Chhatwal, Patrick; Woltemate, Sabrina; Tacconelli, Evelina; Buhl, Michael; Autenrieth, Ingo B; Vehreschild, Maria J G T; Jazmati, Nathalie; Gerhard, Markus; Stein-Thoeringer, Christoph K; Rupp, Jan; Ulm, Kurt; Ott, Armin; Lasch, Florian; Koch, Armin; Manns, Michael P; Suerbaum, Sebastian; Bachmann, Oliver
Abstract:
BACKGROUND: Asymptomatic C. difficile colonization is believed to predispose to subsequent C. difficile infection (CDI). While emerging insights into the role of the commensal microbiota in mediating colonization resistance against C. difficile have associated CDI with specific microbial components, corresponding prospectively collected data on colonization with C. difficile are largely unavailable. METHODS: C. difficile status was assessed by GDH EIA and real-time PCR targeting the toxin A (tcd...     »
Journal title abbreviation:
Clin Infect Dis
Year:
2021
Journal volume:
73
Journal issue:
9
Pages contribution:
e2625-e2634
Fulltext / DOI:
doi:10.1093/cid/ciaa871
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32589701
Print-ISSN:
1058-4838
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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