User: Guest  Login
Title:

Criteria of the German Consortium for Hereditary Breast and Ovarian Cancer for the Classification of Germline Sequence Variants in Risk Genes for Hereditary Breast and Ovarian Cancer.

Document type:
Journal Article; Review
Author(s):
Wappenschmidt, Barbara; Hauke, Jan; Faust, Ulrike; Niederacher, Dieter; Wiesmüller, Lisa; Schmidt, Gunnar; Groß, Evi; Gehrig, Andrea; Sutter, Christian; Ramser, Juliane; Rump, Andreas; Arnold, Norbert; Meindl, Alfons
Abstract:
More than ten years ago, the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) set up a panel of experts (VUS Task Force) which was tasked with reviewing the classifications of genetic variants reported by individual centres of the GC-HBOC to the central database in Leipzig and reclassifying them, where necessary, based on the most recent data. When it evaluates variants, the VUS Task Force must arrive at a consensus. The resulting classifications are recorded in a central dat...     »
Journal title abbreviation:
Geburtsh Frauenheilk
Year:
2020
Journal volume:
80
Journal issue:
4
Pages contribution:
410-429
Fulltext / DOI:
doi:10.1055/a-1110-0909
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32322110
Print-ISSN:
0016-5751
TUM Institution:
1072; 597; Frauenklinik und Poliklinik
 BibTeX