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Title:

On the optimistic performance evaluation of newly introduced bioinformatic methods.

Document type:
Journal Article
Author(s):
Buchka, Stefan; Hapfelmeier, Alexander; Gardner, Paul P; Wilson, Rory; Boulesteix, Anne-Laure
Abstract:
Most research articles presenting new data analysis methods claim that "the new method performs better than existing methods," but the veracity of such statements is questionable. Our manuscript discusses and illustrates consequences of the optimistic bias occurring during the evaluation of novel data analysis methods, that is, all biases resulting from, for example, selection of datasets or competing methods, better ability to fix bugs in a preferred method, and selective reporting of method va...     »
Journal title abbreviation:
Genome Biol
Year:
2021
Journal volume:
22
Journal issue:
1
Fulltext / DOI:
doi:10.1186/s13059-021-02365-4
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33975646
Print-ISSN:
1474-7596
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie; Lehrstuhl für Allgemeinmedizin (Prof. Schneider) (keine SAP-Zuordnung!)
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