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Titel:

A white paper on a neurodevelopmental framework for drug discovery in autism and other neurodevelopmental disorders.

Dokumenttyp:
Review; Journal Article; Review
Autor(en):
Díaz-Caneja, C M; State, M W; Hagerman, R J; Jacquemont, S; Marín, O; Bagni, C; Umbricht, D; Simonoff, E; de Andrés-Trelles, F; Kaale, A; Pandina, G; Gómez-Mancilla, B; Wang, P P; Cusak, J; Siafis, S; Leucht, S; Parellada, M; Loth, E; Charman, T; Buitelaar, J K; Murphy, D; Arango, C
Abstract:
In the last decade there has been a revolution in terms of genetic findings in neurodevelopmental disorders (NDDs), with many discoveries critical for understanding their aetiology and pathophysiology. Clinical trials in single-gene disorders such as fragile X syndrome highlight the challenges of investigating new drug targets in NDDs. Incorporating a developmental perspective into the process of drug development for NDDs could help to overcome some of the current difficulties in identifying and...     »
Zeitschriftentitel:
Eur Neuropsychopharmacol
Jahr:
2021
Band / Volume:
48
Seitenangaben Beitrag:
49-88
Volltext / DOI:
doi:10.1016/j.euroneuro.2021.02.020
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33781629
Print-ISSN:
0924-977X
TUM Einrichtung:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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