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Title:

Soluble High Mobility Group Box 1 (HMGB1) Is a Promising Biomarker for Prediction of Therapy Response and Prognosis in Advanced Lung Cancer Patients.

Document type:
Article; Journal Article
Author(s):
Handke, Nikolaus A; Rupp, Alexander B A; Trimpop, Nicolai; von Pawel, Joachim; Holdenrieder, Stefan
Abstract:
BACKGROUND: High mobility group box 1 protein (HMGB1) is known for its significant elevation in a multitude of tumors and benign diseases. In this study, we investigated the relevance of soluble HMGB1 for the prediction and monitoring of therapy response as well as the estimation of prognosis in advanced lung cancer. MATERIALS AND METHODS: In a retrospective study, HMGB1 levels were assessed by an enzyme-linked immunosorbent assay (ELISA) in the sera of 96 patients with advanced lung cancer (79...     »
Journal title abbreviation:
Diagnostics (Basel)
Year:
2021
Journal volume:
11
Journal issue:
2
Fulltext / DOI:
doi:10.3390/diagnostics11020356
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33672622
TUM Institution:
Institut für Laboratoriumsmedizin (keine SAP-Zuordnung!)
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