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Titel:

Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection.

Dokumenttyp:
Journal Article
Autor(en):
Loffredo-Verde, Eva; Bhattacharjee, Sonakshi; Malo, Antje; Festag, Julia; Kosinska, Anna D; Ringelhan, Marc; Rim Sarkar, Sabrina; Steiger, Katja; Heikenwaelder, Mathias; Protzer, Ulrike; Prazeres da Costa, Clarissa U
Abstract:
BACKGROUND: Chronic hepatitis B develops more frequently in countries with high prevalence of helminth infections. The crosstalk between these 2 major liver-residing pathogens, Schistosoma mansoni and hepatitis B virus (HBV), is barely understood. METHODS: We used state-of-the-art models for both acute and chronic HBV infection to study the pathogen-crosstalk during the different immune phases of schistosome infection. RESULTS: Although liver pathology caused by schistosome infection was not aff...     »
Zeitschriftentitel:
J Infect Dis
Jahr:
2020
Band / Volume:
221
Heft / Issue:
9
Seitenangaben Beitrag:
1448-1461
Volltext / DOI:
doi:10.1093/infdis/jiz594
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31875228
Print-ISSN:
0022-1899
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Institut für Virologie
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