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Titel:

Comparison of the composition of lymphocyte subpopulations in non-relapse and relapse patients with squamous cell carcinoma of the head and neck before, during radiochemotherapy and in the follow-up period: a multicenter prospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).

Dokumenttyp:
Journal Article; Multicenter Study
Autor(en):
Niu, Minli; Combs, Stephanie E; Linge, Annett; Krause, Mechthild; Baumann, Michael; Lohaus, Fabian; Ebert, Nadja; Tinhofer, Ingeborg; Budach, Volker; von der Grün, Jens; Rödel, Franz; Grosu, Anca-Ligia; Multhoff, Gabriele
Abstract:
BACKGROUND: Radiochemotherapy (RCT) has been shown to induce changes in immune cell homeostasis which might affect antitumor immune responses. In the present study, we aimed to compare the composition and kinetics of major lymphocyte subsets in the periphery of patients with non-locoregional recurrent (n = 23) and locoregional recurrent (n = 9) squamous cell carcinoma of the head and neck (SCCHN) upon primary RCT. METHODS: EDTA-blood of non-locoregional recurrent SCCHN patients was collected bef...     »
Zeitschriftentitel:
Radiat Oncol
Jahr:
2021
Band / Volume:
16
Heft / Issue:
1
Volltext / DOI:
doi:10.1186/s13014-021-01868-5
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34332614
Print-ISSN:
1748-717X
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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