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Title:

Quantification of Differential Response of Tumour and Normal Cells to Microbeam Radiation in the Absence of FLASH Effects.

Document type:
Journal Article
Author(s):
Steel, Harriet; Brüningk, Sarah C; Box, Carol; Oelfke, Uwe; Bartzsch, Stefan H
Abstract:
Microbeam radiotherapy (MRT) is a preclinical method of delivering spatially-fractionated radiotherapy aiming to improve the therapeutic window between normal tissue complication and tumour control. Previously, MRT was limited to ultra-high dose rate synchrotron facilities. The aim of this study was to investigate in vitro effects of MRT on tumour and normal cells at conventional dose rates produced by a bench-top X-ray source. Two normal and two tumour cell lines were exposed to homogeneous bro...     »
Journal title abbreviation:
Cancers (Basel)
Year:
2021
Journal volume:
13
Journal issue:
13
Fulltext / DOI:
doi:10.3390/cancers13133238
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34209502
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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