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Title:

Early detection of radiation-induced lung damage with X-ray dark-field radiography in mice.

Document type:
Journal Article
Author(s):
Burkhardt, Rico; Gora, Thomas; Fingerle, Alexander A; Sauter, Andreas P; Meurer, Felix; Umkehrer, Stephan; von Teuffenbach, Maximilian; Kampfer, Severin; Schilling, Daniela; Feuchtinger, Annette; Walch, Axel K; Rummeny, Ernst; Combs, Stephanie E; Schmid, Thomas E; Pfeiffer, Franz; Wilkens, Jan J; Herzen, Julia
Abstract:
OBJECTIVE: Assessing the advantage of x-ray dark-field contrast over x-ray transmission contrast in radiography for the detection of developing radiation-induced lung damage in mice. METHODS: Two groups of female C57BL/6 mice (irradiated and control) were imaged obtaining both contrasts monthly for 28 weeks post irradiation. Six mice received 20 Gy of irradiation to the entire right lung sparing the left lung. The control group of six mice was not irradiated. A total of 88 radiographs of both co...     »
Journal title abbreviation:
Eur Radiol
Year:
2021
Journal volume:
31
Journal issue:
6
Pages contribution:
4175-4183
Fulltext / DOI:
doi:10.1007/s00330-020-07459-4
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33211140
Print-ISSN:
0938-7994
TUM Institution:
Institut für Diagnostische und Interventionelle Radiologie; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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