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Title:

Narrative review: prostate-specific membrane antigen-radioligand therapy in metastatic castration-resistant prostate cancer.

Document type:
Journal Article; Review
Author(s):
Lunger, Lukas; Tauber, Robert; Feuerecker, Benedikt; Gschwend, Jürgen E; Eiber, Matthias; Heck, Matthias M
Abstract:
Radioactive-labelled ligands targeting the prostate-specific membrane antigen (PSMA), a transmembrane protein overexpressed in prostate cancer (PC), have shown promising activity in treatment of metastatic castration-resistant prostate cancer (mCRPC). PSMA-617 and PSMA-I&T; (imaging and therapy), both labeled to the beta-emitter lutetium-177 (Lu177), are most frequently used in clinical routine and have shown a favorable side-effect profile. Common side effects are transient xerostomia. Severe sid...     »
Journal title abbreviation:
Transl Androl Urol
Year:
2021
Journal volume:
10
Journal issue:
10
Pages contribution:
3963-3971
Fulltext / DOI:
doi:10.21037/tau-20-1135
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34804839
Print-ISSN:
2223-4683
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin; Urologische Klinik und Poliklinik
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