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Title:

PSMA-PET/MRI-Based Focal Dose Escalation in Patients with Primary Prostate Cancer Treated with Stereotactic Body Radiation Therapy (HypoFocal-SBRT): Study Protocol of a Randomized, Multicentric Phase III Trial.

Document type:
Journal Article
Author(s):
Zamboglou, Constantinos; Spohn, Simon K B; Adebahr, Sonja; Huber, Maria; Kirste, Simon; Sprave, Tanja; Gratzke, Christian; Chen, Ronald C; Carl, Ernst Günther; Weber, Wolfgang A; Mix, Michael; Benndorf, Matthias; Wiegel, Thomas; Baltas, Dimos; Jenkner, Carolin; Grosu, Anca L
Abstract:
Technical advances in radiotherapy (RT) treatment planning and delivery have substantially changed RT concepts for primary prostate cancer (PCa) by (i) enabling a reduction of treatment time, and by (ii) enabling safe delivery of high RT doses. Several studies proposed a dose-response relationship for patients with primary PCa and especially in patients with high-risk features, as dose escalation leads to improved tumor control. In parallel to the improvements in RT techniques, diagnostic imagin...     »
Journal title abbreviation:
Cancers (Basel)
Year:
2021
Journal volume:
13
Journal issue:
22
Fulltext / DOI:
doi:10.3390/cancers13225795
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34830950
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin
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