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Titel:

X-Ray Dark-field Imaging to Depict Acute Lung Inflammation in Mice.

Dokumenttyp:
Journal Article
Autor(en):
Hellbach, Katharina; Meinel, Felix G; Conlon, Thomas M; Willer, Konstantin; Yaroshenko, Andre; Velroyen, Astrid; Braunagel, Margarita; Auweter, Sigrid; Reiser, Maximilian F; Eickelberg, Oliver; Pfeiffer, Franz; Yildirim, Ali Ö
Abstract:
The aim of this study was to evaluate the feasibility of early stage imaging of acute lung inflammation in mice using grating-based X-ray dark-field imaging in vivo. Acute lung inflammation was induced in mice by orotracheal instillation of porcine pancreatic elastase. Control mice received orotracheal instillation of PBS. Mice were imaged immediately before and 1 day after the application of elastase or PBS to assess acute changes in pulmonary structure due to lung inflammation. Subsequently, 6...     »
Zeitschriftentitel:
Sci Rep
Jahr:
2018
Band / Volume:
8
Heft / Issue:
1
Seitenangaben Beitrag:
2096
Volltext / DOI:
doi:10.1038/s41598-018-20193-8
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29391514
Print-ISSN:
2045-2322
TUM Einrichtung:
Institut für Diagnostische und Interventionelle Radiologie
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