Outcomes of endovascular treatment for infrapopliteal peripheral artery disease based on the updated TASC II classification.

Müller, Arne M; Räpple, Veronika; Bradaric, Christian; Koppara, Tobias; Kehl, Victoria; Fusaro, Massimiliano; Cassese, Salvatore; Ott, Ilka; Kastrati, Adnan; Laugwitz, Karl-Ludwig; Ibrahim, Tareq

doi:10.1177/1358863X20967091

2021

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Document type:: Article; Journal Article
Author(s):: Müller, Arne M; Räpple, Veronika; Bradaric, Christian; Koppara, Tobias; Kehl, Victoria; Fusaro, Massimiliano; Cassese, Salvatore; Ott, Ilka; Kastrati, Adnan; Laugwitz, Karl-Ludwig; Ibrahim, Tareq
Title:: Outcomes of endovascular treatment for infrapopliteal peripheral artery disease based on the updated TASC II classification.
Abstract:: We retrospectively analyzed all endovascular procedures of infrapopliteal arterial lesions (n = 383) performed in 270 patients at our institution between December 2008 and January 2018. The overall technical success rate was 97% and yielded 98% for stenoses (n = 214) and 95% for occlusions (n = 169). Trans-Atlantic Inter-Society Consensus (TASC II) classification had no impact on success rates (TASC A + B vs C + D; 96.5% vs 96.9%, p = 0.837). Freedom from clinically driven target lesion revascularization (TLR) after 6 and 12 months was 88.3% and 77.2%. TLR was comparable for TASC A to C lesions and no difference was observed comparing groups of moderately complex TASC A/B lesions and more complex TASC C/D lesions (TASC A + B vs C + D; 78.5% vs 74.2%, p = 0.457). Freedom from TLR was significantly lower in very complex TASC D lesions (TASC A + B + C vs D; 79.7% vs 42.5%, p < 0.001). Multivariate analysis identified TASC D lesions (hazard ratio D/A: 1.5; overall p = 0.002), Fontaine class III and IV (hazard ratio III or IV/IIa or IIb: 2.4; p = 0.041), and occlusive lesions (hazard ratio occlusion/stenosis: 2.4; p = 0.026) as predictors for TLR. In conclusion, endovascular therapy for infrapopliteal artery disease was safe and accompanied with a promising long-term outcome.
Journal title abbreviation:: Vasc Med
Year:: 2021
Journal volume:: 26
Journal issue:: 1
Pages contribution:: 18-25
Fulltext / DOI:: doi:10.1177/1358863X20967091
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/33256573
Print-ISSN:: 1358-863X
TUM Institution:: Institut für Medizinische Statistik und Epidemiologie; Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert); Klinik und Poliklinik für Innere Medizin I, Kardiologie
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