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Titel:

Tumor-associated collagen signatures: pushing tumor boundaries.

Dokumenttyp:
Journal Article; Review
Autor(en):
Brett, Elizabeth A; Sauter, Matthias A; Machens, Hans-Günther; Duscher, Dominik
Abstract:
In 2006, a new model of invasive breast tumor emerged and, since 2011, is gaining recognition and research momentum. "Tumor-associated collagen signatures" describe 3 distinct layers of collagen which radiate outward in shells from the main body of the tumor. The outermost layer (TACS3) features branches of collagen radiating away from the tumor, 90° perpendicular to the tumor surface. TACS3 increases tumor span and correlates directly with metastasis, though presently difficult to detect in bre...     »
Zeitschriftentitel:
Cancer Metab
Jahr:
2020
Band / Volume:
8
Volltext / DOI:
doi:10.1186/s40170-020-00221-w
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32637098
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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