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Titel:

Efficacy and safety of treatment with omalizumab for chronic spontaneous urticaria: A systematic review for the EAACI Biologicals Guidelines.

Dokumenttyp:
Journal Article
Autor(en):
Agache, Ioana; Rocha, Claudio; Pereira, Ana; Song, Yang; Alonso-Coello, Pablo; Solà, Ivan; Beltran, Jessica; Posso, Margarita; Akdis, Cezmi; Akdis, Mubeccel; Brockow, Knut; Chivato, Tomas; Del Giacco, Stefano; Eiwegger, Thomas; Eyerich, Kilian; Giménez-Arnau, Ana; Gutermuth, Jan; Guttman-Yassky, Emma; Maurer, Marcus; Ogg, Graham; Ong, Peck; O'Mahony, Liam; Schwarze, Jürgen; Werfel, Thomas; Canelo-Aybar, Carlos; Palomares, Oscar; Jutel, Marek
Abstract:
This systematic review evaluates the efficacy and safety of omalizumab for chronic spontaneous urticaria (CSU). PubMed, Embase, and Cochrane Library were searched for RCTs. Critical and important CSU-related outcomes were considered. The risk of bias and the certainty of the evidence were assessed using GRADE. Ten RCTs including 1620 subjects aged 12 to 75 years old treated with omalizumab for 16 to 40 weeks were evaluated. Omalizumab 150 mg does not result in clinically meaningful improvement (...     »
Zeitschriftentitel:
Allergy
Jahr:
2021
Band / Volume:
76
Heft / Issue:
1
Seitenangaben Beitrag:
59-70
Volltext / DOI:
doi:10.1111/all.14547
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32767573
Print-ISSN:
0105-4538
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie; Professur für Experimentelle Dermato-Immunologie (Prof. Eyerich)
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