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Title:

Efficacy and safety of dupilumab for moderate-to-severe atopic dermatitis: A systematic review for the EAACI biologicals guidelines.

Document type:
Journal Article
Author(s):
Agache, Ioana; Song, Yang; Posso, Margarita; Alonso-Coello, Pablo; Rocha, Claudio; Solà, Ivan; Beltran, Jessica; Akdis, Cezmi; Akdis, Mubeccel; Brockow, Knut; Chivato, Tomas; Del Giacco, Stefano; Eiwegger, Thomas; Eyerich, Kilian; Giménez-Arnau, Ana; Gutermuth, Jan; Guttman-Yassky, Emma; Maurer, Marcus; Ogg, Graham; Ong, Peck Y; O'Mahony, Liam; Schwarze, Jürgen; Werfel, Thomas; Canelo-Aybar, Carlos; Palomares, Oscar; Jutel, Marek
Abstract:
This systematic review evaluates the efficacy, safety and economic impact of dupilumab compared to standard of care for uncontrolled moderate-to-severe atopic dermatitis (AD). Pubmed, EMBASE and Cochrane Library were searched for RCTs and health economic evaluations. Critical and important AD-related outcomes were considered. The risk of bias and the certainty of the evidence were assessed using GRADE. Seven RCTs including 1845 subjects >12 years treated with dupilumab 16 to 52 weeks were evalua...     »
Journal title abbreviation:
Allergy
Year:
2021
Journal volume:
76
Journal issue:
1
Pages contribution:
45-58
Fulltext / DOI:
doi:10.1111/all.14510
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32691892
Print-ISSN:
0105-4538
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie; Professur für Experimentelle Dermato-Immunologie (Prof. Eyerich)
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