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Titel:

Regulation of Cell Death and Immunity by XIAP.

Dokumenttyp:
Article; Journal Article; Review
Autor(en):
Jost, Philipp J; Vucic, Domagoj
Abstract:
X-chromosome-linked inhibitor of apoptosis protein (XIAP) controls cell survival in several regulated cell death pathways and coordinates a range of inflammatory signaling events. Initially identified as a caspase-binding protein, it was considered to be primarily involved in blocking apoptosis from both intrinsic as well as extrinsic triggers. However, XIAP also prevents TNF-mediated, receptor-interacting protein 3 (RIPK3)-dependent cell death, by controlling RIPK1 ubiquitylation and preventing...     »
Zeitschriftentitel:
Cold Spring Harb Perspect Biol
Jahr:
2020
Band / Volume:
12
Heft / Issue:
8
Volltext / DOI:
doi:10.1101/cshperspect.a036426
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31843992
Print-ISSN:
1943-0264
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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