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Title:

miR-181c level predicts response to exercise training in patients with heart failure and preserved ejection fraction: an analysis of the OptimEx-Clin trial.

Document type:
Article; Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Gevaert, Andreas B; Witvrouwen, Isabel; Van Craenenbroeck, Amaryllis H; Van Laere, Steven J; Boen, Jente R A; Van de Heyning, Caroline M; Belyavskiy, Evgeny; Mueller, Stephan; Winzer, Ephraim; Duvinage, André; Edelmann, Frank; Beckers, Paul J; Heidbuchel, Hein; Wisløff, Ulrik; Pieske, Burkert; Adams, Volker; Halle, Martin; Van Craenenbroeck, Emeline M
Abstract:
AIMS: In patients with heart failure with preserved ejection fraction (HFpEF), exercise training improves the quality of life and aerobic capacity (peakV·O2). Up to 55% of HF patients, however, show no increase in peakV·O2 despite adequate training. We hypothesized that circulating microRNAs (miRNAs) can distinguish exercise low responders (LR) from exercise high responders (HR) among HFpEF patients. METHODS AND RESULTS: We selected HFpEF patients from the Optimizing Exercise Training in Prevent...     »
Journal title abbreviation:
Eur J Prev Cardiol
Year:
2021
Journal volume:
28
Journal issue:
15
Pages contribution:
1722-1733
Fulltext / DOI:
doi:10.1093/eurjpc/zwab151
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34508569
Print-ISSN:
2047-4873
TUM Institution:
Poliklinik für Präventive und Rehabilitative Sportmedizin
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