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Titel:

Quantitative and Qualitative Analyses of Biodistribution and PET Image Quality of a Novel Radiohybrid PSMA, 18F-rhPSMA-7, in Patients with Prostate Cancer.

Dokumenttyp:
Journal Article
Autor(en):
Oh, So Won; Wurzer, Alexander; Teoh, Eugene J; Oh, Sohee; Langbein, Thomas; Krönke, Markus; Herz, Michael; Kropf, Saskia; Wester, Hans-Jürgen; Weber, Wolfgang A; Eiber, Matthias
Abstract:
Radiohybrid PSMA (rhPSMA) ligands, a new class of theranostic prostate-specific membrane antigen (PSMA)-targeting agents, feature fast 18F synthesis and utility for labeling with radiometals. Here, we assessed the biodistribution and image quality of 18F-rhPSMA-7 to determine the best imaging time point for patients with prostate cancer. Methods: In total, 202 prostate cancer patients who underwent a clinically indicated 18F-rhPSMA-7 PET/CT were retrospectively analyzed, and 12 groups based on t...     »
Zeitschriftentitel:
J Nucl Med
Jahr:
2020
Band / Volume:
61
Heft / Issue:
5
Seitenangaben Beitrag:
702-709
Volltext / DOI:
doi:10.2967/jnumed.119.234609
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31836686
Print-ISSN:
0161-5505
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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