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Title:

Placebo response in pharmacological and dietary supplement trials of autism spectrum disorder (ASD): systematic review and meta-regression analysis.

Document type:
Review; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Siafis, Spyridon; Çıray, Oğulcan; Schneider-Thoma, Johannes; Bighelli, Irene; Krause, Marc; Rodolico, Alessandro; Ceraso, Anna; Deste, Giacomo; Huhn, Maximilian; Fraguas, David; Mavridis, Dimitris; Charman, Tony; Murphy, Declan G; Parellada, Mara; Arango, Celso; Leucht, Stefan
Abstract:
BACKGROUND: Placebo response in autism spectrum disorder (ASD) might dilute drug-placebo differences and hinder drug development. Therefore, this meta-analysis investigated placebo response in core symptoms. METHODS: We searched ClinicalTrials.gov , CENTRAL, EMBASE, MEDLINE, PsycINFO, WHO-ICTRP (up to July 8, 2018), and PubMed (up to July 4, 2019) for randomized pharmacological and dietary supplement placebo-controlled trials (RCTs) with a minimum of seven days of treatment. Single-group meta-an...     »
Journal title abbreviation:
Mol Autism
Year:
2020
Journal volume:
11
Journal issue:
1
Fulltext / DOI:
doi:10.1186/s13229-020-00372-z
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32847616
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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