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- Title:
Metabolic Precision Medicines: Curing POMC Deficiency.
- Document type:
- Journal Article; Editorial Material
- Author(s):
- Müller, Timo D; Tschöp, Matthias H; O'Rahilly, Stephen
- Abstract:
- Pro-opiomelanocortin deficiency is a rare cause of severe intractable obesity. Two patients have experienced dramatic weight loss in response to setmelanotide, a melanocortin-4 receptor activator. The drug has potential in broader populations, but caution is warranted as it may act at other melanocortin receptors.
- Journal title abbreviation:
- Cell Metab
- Year:
- 2016
- Journal volume:
- 24
- Journal issue:
- 2
- Pages contribution:
- 194-5
- Fulltext / DOI:
- doi:10.1016/j.cmet.2016.07.006
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/27452145
- Print-ISSN:
- 1550-4131
- TUM Institution:
- Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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