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Title:

Immunization with a recombinant fusion protein protects mice against Helicobacter pylori infection.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Ghasemi, Amir; Mohammad, Nazanin; Mautner, Josef; Taghipour Karsabet, Mehrnaz; Amani, Jafar; Ardjmand, Abolfazl; Vakili, Zarichehr
Abstract:
More than 50% of the world's population is infected with the bacterium Helicobacter pylori. If left untreated, infection with H. pylori can cause chronic gastritis and peptic ulcer disease, which may progress into gastric cancer. Owing to the limited efficacy of anti-H. pylori antibiotic therapy in clinical practice, the development of a protective vaccine to combat this pathogen has been a tempting goal for several years. In this study, a chimeric gene coding for the antigenic parts of H. pylor...     »
Journal title abbreviation:
Vaccine
Year:
2018
Journal volume:
36
Journal issue:
34
Pages contribution:
5124-5132
Fulltext / DOI:
doi:10.1016/j.vaccine.2018.07.033
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30041879
Print-ISSN:
0264-410X
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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