Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: in-hospital data and 1-year results from the German Aortic Valve Registry (GARY).

Bekeredjian, Raffi; Szabó, Gábor; Balaban, Ümniye; Bleiziffer, Sabine; Bauer, Timm; Ensminger, Stephan; Frerker, Christian; Herrmann, Eva; Beyersdorf, Friedhelm; Hamm, Christian; Beckmann, Andreas; Möllmann, Helge; Karck, Matthias; Katus, Hugo A; Walther, Thomas

doi:10.1093/eurheartj/ehy699

journal article

Title:: Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: in-hospital data and 1-year results from the German Aortic Valve Registry (GARY).
Document type:: Journal Article
Author(s):: Bekeredjian, Raffi; Szabó, Gábor; Balaban, Ümniye; Bleiziffer, Sabine; Bauer, Timm; Ensminger, Stephan; Frerker, Christian; Herrmann, Eva; Beyersdorf, Friedhelm; Hamm, Christian; Beckmann, Andreas; Möllmann, Helge; Karck, Matthias; Katus, Hugo A; Walther, Thomas
Abstract:: AIMS: Transcatheter aortic valve implantation (TAVI) has become the standard treatment for patients with severe aortic valve stenosis at high surgical risk and may be considered for patients with intermediate risk. During the last few years, an increasing number of patients with low surgical risk have been treated with TAVI. In this study, low-risk patients undergoing isolated TAVI or surgical aortic valve replacement (SAVR) were analysed using data from the German Aortic Valve Registry (GARY). METHODS AND RESULTS: All patients with a Society of Thoracic Surgeons Score of <4% undergoing TAVI or SAVR in 2014 and 2015 were evaluated. A total of 20 549 low surgical risk patients remained for further analysis, comprising 14 487 surgical patients and 6062 TAVI patients. Since TAVI patients were significantly older and had significantly more co-morbidities, a weighted propensity score model was used to compare SAVR and TAVI patients for in-hospital, 30-day, and 1-year mortality. Transcatheter aortic valve implantation patients showed a significantly higher in-hospital and 30-day survival than SAVR patients (in hospital survival TAVI vs. SAVR: 98.5% vs. 97.3%; P = 0.003; 30-day survival TAVI vs. SAVR: 98.1% vs. 97.1%; P = 0.014). At 1 year, survival rates did not differ significantly (survival TAVI vs. SAVR: 90.0% vs. 91.2%; P = 0.158). CONCLUSION: In this first GARY analysis of low-risk patients, weighted comparison showed similar 1-year survival for TAVI and SAVR and higher in-hospital survival for TAVI patients.
Journal title abbreviation:: Eur Heart J
Year:: 2019
Journal volume:: 40
Journal issue:: 17
Pages contribution:: 1323-1330
Fulltext / DOI:: doi:10.1093/eurheartj/ehy699
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/30445543
Print-ISSN:: 0195-668X
TUM Institution:: Klinik für Herz- und Gefäßchirurgie (Prof. Lange)
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mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Lehr- und Forschungskooperationen mit den Kliniken und Instituten am Deutschen Herzzentrum Klinik für Herz- und Gefäßchirurgie (DHM) (Prof. Krane)2019