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Title:

Renaissance of leptin for obesity therapy.

Document type:
Journal Article; Review; Review
Author(s):
Quarta, Carmelo; Sánchez-Garrido, Miguel A; Tschöp, Matthias H; Clemmensen, Christoffer
Abstract:
Diet-induced obesity and its metabolic comorbidities constitute an overwhelming health crisis and there is an urgent need for safe and effective pharmacological interventions. Being largely shelved for decades, scientists are now revisiting the anti-obesity virtues of leptin. Whereas it remains evident that leptin as a stand-alone therapy is not an effective approach, the potential for employing sensitising pharmacology to unleash the weight-lowering properties of leptin has injected new hope in...     »
Journal title abbreviation:
Diabetologia
Year:
2016
Journal volume:
59
Journal issue:
5
Pages contribution:
920-7
Fulltext / DOI:
doi:10.1007/s00125-016-3906-7
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26983921
Print-ISSN:
0012-186X
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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